Here is a color still photo of the speech.
In contrast, here is a video of FDR speaking in October 1944, less than three months prior to the State of the Union video. There are a few minor stumbles, but his hands remain at his side. The contrast is remarkable.
On March 1, 1945 FDR give the worst performance of his life during his speech to congress, deviating from the prepared text, (according to the New York Times, 49 times, we never counted) due to a primarily left sided visual deficit. On April 12, he died of a massive cerebral hemorrhage emanating from the right posterior portion of his brain- the area that controls the left side of vision.